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Background 3: In vivo experiment Outline ?Modeling in addition to simulation of cancer immunoprevention vaccine? by F.Pappalardo et al
California School of Professional Psychology – San Diego, US has reference to this Academic Journal, ?Modeling in addition to simulation of cancer immunoprevention vaccine? by F.Pappalardo et al Summary by Dhondup Pemba SoCalBSI Outline Background Motivation Method Results Conclusion Background 2:Cancer Immunoprevention Cervical Cancer Papilloma Vaccination Hepatocellular Carcinoma Hepatitis B Vaccination Tumors not linked so that viruses?
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Background 3: In vivo experiment HER2 Transgenic mouse Triplex Vaccine 5 Vaccination Protocols Early ? 6 weeks Late ? 10 weeks Very late ? 16 weeks Chronic- 6 weeks alongside repetition Untreated Motivation Determining optimal vaccination protocol Method: Model type Modified Lattice Gas Automata Class of Dynamical Systems Particles move in discrete time steps Stochastic relationship between interacting entities
Method: Internal States Method: Interactions Method: Model Algorithm SimTriplex Simulator Initialization Iteration Interaction Dynamics Internal Dynamics Output
Overview Outline IR in addition to relational databases Structured Retrieval Outline XML document XML document XML document XML document XML basics Outline Outline Outline
Results 1: Results 2 Results 4
Results 3 Conclusion: Excellent agreement between in vivo in addition to in silico models Important Biological point that can be further examined Antibodies instead of T cells as the control of tumor growth Future expansion so that predict vaccination schedules Saves time Money
Elias, Thomas Host
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Journal Ratings by California School of Professional Psychology – San Diego
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