Dr Sam Gausden FY2 February 2015 Inflammatory bowel disease Contents/aims/object

Dr Sam Gausden FY2 February 2015 Inflammatory bowel disease Contents/aims/object www.phwiki.com

Dr Sam Gausden FY2 February 2015 Inflammatory bowel disease Contents/aims/object

Grammer, Geoff, High School Sports Editor has reference to this Academic Journal, PHwiki organized this Journal Dr Sam Gausden FY2 February 2015 Inflammatory bowel disease Contents/aims/objectives Definition Presentation Investigations Management Clinical scenario Explanation station Definition

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Definition Umbrella term Definition Umbrella term Chronic Definition Umbrella term Chronic Relapsing-remitting

Definition Umbrella term Chronic Relapsing-remitting Acute non-infectious inflammation Differences Differences Distribution

Differences Differences Distribution Smoking Smoking in IBD 2/3 Crohn’s pts are smokers in addition to cessation halves relapse 95% of UC pts are non-smokers or ex-smokers

Smoking in IBD YOU SEE people smoking with UC Smoking in Crohn’s makes you want to GROAN Differences Distribution Smoking Histology UC histology

UC histology Hyperaemic/haemorrhagic colonic mucosa Pseudopolyps Usually on affects mucosal layer Absence of goblet cells Crohn’s histology Transmural granulomatous inflammation Cobblestoning MACROSCOPICALLY: Strictures, abscesses, fistulae, skip lesions Systemic manifestations

Systemic manifestations Hepatic – autoimmune hepatitis (UC), gallstones (Cr), PSC (UC) Systemic manifestations Hepatic Other – VTE, osteoporosis (Cr), amyloidosis (Cr) Systemic manifestations Hepatic Other Rheum – arthritis, sacro-ileitis, AS

Systemic manifestations Hepatic Other Rheum Skin – EN in addition to PG (UC>Cr) Systemic manifestations Hepatic Other Rheum Skin Eyes – iritis, uveitis Eyes Uveal tract = iris, ciliary body in addition to choroid

Grammer, Geoff Tucson Citizen High School Sports Editor www.phwiki.com

Systemic manifestations H epatic O ther R heum S kin E yes Symptoms – UC Symptoms – UC Diarrhoea + blood/mucous Faecal urgency/incontinence Tenesmus Lower abdominal pain Tiredness/malaise Weight loss/failure to thrive or grow Fever

Symptoms – Crohn’s Symptoms – Crohn’s Diarrhoea +/- blood/mucous Malabsorption Abdominal pain (crampy) Mouth ulcers Bowel obstruction Fistulas (perianal) Abscesses (perianal/intrabdominal) Tiredness/malaise Weight loss/failure to thrive or grow Fever Signs – UC

Always remember as long as IBD Ask about eyes, joints in addition to skin Only ever do flexi sig in an acute flare If in doubt over diagnosis, say IBD Know difference between ileostomy in addition to colostomy Test as long as TB be as long as e starting infliximab Any questions References 1) http://www.nice.org.uk/guidance/conditions- in addition to -diseases/digestive-tract-conditions/inflammatory-bowel-disease

Grammer, Geoff High School Sports Editor

Grammer, Geoff is from United States and they belong to Tucson Citizen and they are from  Tucson, United States got related to this Particular Journal. and Grammer, Geoff deal with the subjects like High School Sports

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This Particular Journal got reviewed and rated by Bloomfield College and short form of this particular Institution is US and gave this Journal an Excellent Rating.