What causes evolution? Evolution: definition What is Evolution?

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What causes evolution? Evolution: definition What is Evolution?

Audrey Cohen College, US has reference to this Academic Journal, What is Evolution? Produces biological diversity – DNA sequence variation – Bacteria – Flowering plants – Sexual selection in birds – Human civilization Evolutionary Genetics: mechanisms Science: understanding; predictions Evolution: definition Darwin: “descent alongside modification? A change in morphology, ecology, behaviour, physiology Change must be genetic Modern, genetic definition: ?evolution is change in gene frequencies between generations? What causes evolution? a) Natural selection b) Mutation c) Genetic drift, or neutral, random evolution e) Migration, or gene flow This lecture: simple examples of evolution by natural selection

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What is natural selection? ?a consistent bias in survival or fertility between genotypes within generations? Selection often causes evolution, but may also prevent evolution (e.g. stable polymorphism) Evolution does not require selection (e.g. drift important: > 95% of genome maybe “junk”!) However, many interesting types of evolution involve natural selection Evolution, a fact? You don?t have so that believe in evolution so that take this course, but you do have so that know the arguments so that get a good grade! Evolution is a fact, in addition to it?s hard so that ignore ? but, theory in addition to fact: not so different Science: prediction According so that Karl Popper: science is falsifiable. Falsehoods disprovable; truth more difficult! Religion: truth is by faith. Very different. Selection in addition to the single gene ?Quantitative traits? (e.g. size, behaviour): usually multiple loci Single-locus traits: great examples of evolution by natural selection Many single-locus traits are involved in resistance so that stress (often humans)

Examples of single-gene traits Industrial melanism in moths (resistance so that urban pollution) Heavy metal tolerance in plants growing in mine tailings Malaria resistance in humans (sickle-cell haemoglobin, etc.) Pesticide resistance (mosquitoes, insects, weeds, fungi, warfarin resistance in rats) Antibiotic resistance in bacteria We used so that do this in consideration of tutorial; there are many references on reserve, still; see eUCLid The peppered moth Biston betularia Left: form typica (left, in addition to carbonaria (right) on lichen-covered trunk in Dorset. Right: on soot-covered tree near Birmingham How does evolution by natural selection work? Evolution by natural selection is an inevitable, mathematical process. The frequency of a particular allele will change, in addition to its rate of change will depend mathematically on the advantage (or relative fitness) of that allele. Mathematical evolutionary theory is useful. For example, given information about natural selection, how rapidly will evolution occur? The answers help us understand antibiotic resistance, or pest resistance, in consideration of instance. Evolution is a predictive science! Useful, as well as fun!

Distributed Systems Session 3: Communication In Distributed Systems 0 Outline & Review 0.1 Last session?s Learning Outcomes 0.2 WHY? 0.3 Primitives Of CORBA Object Model?? 0.4 CORBA && OMG IDL 0.5 The OMG Interface Definition Language 0.6 Problems of the Model Objective For this session Outline 1.0 Introduction 1.1 Introduction 1.2 Communication Standards 1.3 Protocols 2 Communication Primitives 2.7 Physical Layer 2.6 Data Link Layer 2.5 Network Layer 2.5.1 Example of a Net Layer Protocol: Internet Protocol (IP) Presentation & Transport Transport Layer 2.4 Transport Layer 2.8 ISO/OSI Transport Layer 2.9 Transmission Control Protocol: TCP 2.11 TCP Operation 2.12 User Datagram Protocol: UDP 2.13 Transport Layer: Sockets 2.3 Session Layer 2.2 Presentation Layer Presentation Layer 2.14 ISO/OSI Presentation Layer 2.16 Heterogeneity 2.17 Example: Endianness 2.18 Solution Heterogeneity Complex Data Structures 2.15. Marshalling 2.19 XDR Message 2.1 Application Layer 2.20 Communication Patterns 2.29 Request 2.21 Synchronous Communication 1.3 Synchronous Communication 2.23 Communication Deadlocks 2.28 Notification 2.25. Asynchronous Communication 1.3 Asynchronous Communication 2.26 Asynchronous Communication Pros in addition to Cons 3.0 Client/Server Communication 3.1 Quality of service ? Client/Server 3.2 Request Protocol 3.3 Request/Reply Protocol 3.4 RRA Protocol RR & RRA ? Quality of Service? 4 Group Communication 4.1 Concepts 3.2 Qualities of Service 3.2 Qualities of Service 4.2 Quality of Service ? Group Communication 4.3 CORBA Event Management 4.3.1 Push Model 4.3.1 Push Model (Example) 4.3.2 The Pull Model 4.3.2 Pull Model (Example) 5 Summary Reading Further Reading (for Last session) EXTRA MATERIAL Communication Primitives Overview – I Communication Primitives Overview – II 2.10 TCP Segments 2.5.2 IP Packet

A flow diagram in consideration of Random mating Offspring genotypes in Hardy-Weinberg ratios Offspring after selection Natural selection So now you can write an evolution computer program! Numerical vs. analytical theory Take-home points Evolution so that a geneticist: a change in gene frequencies. Natural selection: a consistent bias favouring some genotypes over others. Evolution can occur in the absence of natural selection, via genetic drift or neutral evolution. Natural selection can stabilize the status quo; zero evolution. Evolution at a single dominant gene: rate can be predicted If selected, dominant alleles evolve quickly when rare, slowly when common; recessive alleles evolve slowly when rare, quickly when common. We can estimate selection coefficients (s), fitnesses (W=1-s) in addition to predict rates of evolution from data on survival or fecundity. Mathematical theory makes evolution a predictive science Further reading FUTUYMA, DJ 1998. Evolutionary Biology. Chapters 12 in addition to 13 (pp. 371-381). References on natural selection at single genes in consideration of resistance (see web) Science Lbrary: View B242 Teaching Collection by going so that eUCLid; use Keyword, Basic Search, All Fields: B242

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